Describe how the structure of macromolecules affects their function?

Macromolecules, in simple terms, are long polymers.  Polymers are made up of basic building blocks called monomers.  When monomers link together, they form polymers.  According to the structure of the macromolecules, the functional group of the molecules change and affect the function of the macromolecule.  Functional group and the structure first affect the monomers of the macromolecules.  For example, although glucose and fructose are all six carbon sugar with the exact same functional groups, but the isomer, or the shape of the monomer change its function.  When monomers link, the way they link may affect the macromolecule.  For example, when cysteine (amino acids) link to form a peptide, cysteine forms disulfide bonds.  This is one of the special function of protein because protein is able to coil and fold based on the numerous bonds in the peptides.   The structure of macromolecule, such as protein, affect the function.  For a macromolecule like protein, protein only functions when the protein is in its folded structure.  If a protein is to denature and unfold, the protein would not even work.  Enzymes only work under a certain conditions, and if enzymes are to denature, then enzymes will no longer catalyze substrates.